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Medchemexpress LLC D-GsMTx4 | 1209500-46-8 | 99.4% | 4095.84 | 1 MG
Supplier: Medchemexpress LLC HYP1410B1MG
D-GsMTx4 is a spider peptide that serves as the D enantiomer of GsMTx4. This compound is a potent inhibitor of the mechanosensitive ion channel Piezo2, making it a valuable tool in neuroscience research. It has demonstrated inhibitory effects on intracellular calcium ([Ca2+]i) elevation, as well as the mTOR and PI3K-Akt signaling pathways. Research indicates its potential in mitigating mechanical allodynia and thermal hyperalgesia. D-GsMTx4 is utilized in studies exploring mechanical stress, chronic pain, and idiopathic pulmonary fibrosis.
- Inhibits mechanosensitive ion channel Piezo2
- Inhibits [Ca2+]i elevation
- Inhibits mTOR and PI3K-Akt signaling pathways
- Potentially mitigates mechanical allodynia and thermal hyperalgesia
- Used in research of mechanical stress, chronic pain, and idiopathic pulmonary fibrosis
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