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Medchemexpress LLC D-GsMTx4 | 1209500-46-8 | 99.4% | 4095.84 | 500 UG
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Supplier:  Medchemexpress LLC HYP1410B500UG

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D-GsMTx4 is a spider peptide and the D enantiomer of GsMTx4. It functions as an inhibitor of the mechanosensitive ion channel Piezo2. It also inhibits [Ca2+]i elevation and the mTOR and PI3K-Akt signaling pathways. This compound has been used in research related to mechanical stress, chronic pain, and idiopathic pulmonary fibrosis, and inhibits mechanical allodynia and thermal hyperalgesia.

  • Inhibits mechanosensitive ion channel Piezo2
  • Decreases phosphorylation levels of proteins in mTOR and PI3K-Akt signaling pathways
  • Inhibits mechanical stimulation-evoked calcium increases
  • Significantly inhibits mechanical allodynia and thermal hyperalgesia
  • Used in research for mechanical stress, chronic pain, and idiopathic pulmonary fibrosis

Catalog No. 50-004-23083


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