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Medchemexpress LLC D-GsMTx4 | 99.4% | 4095.84 | 100 UG
Supplier: Medchemexpress LLC HYP1410B100UG
D-GsMTx4 is a spider peptide and the D enantiomer of GsMTx4. It acts as an inhibitor of the mechanosensitive ion channel Piezo2. It inhibits [Ca2+]i elevation and also impacts the mTOR and PI3K-Akt signaling pathways. D-GsMTx4 has been shown to inhibit mechanical allodynia and thermal hyperalgesia. It is suitable for research in areas such as mechanical stress, chronic pain, and idiopathic pulmonary fibrosis.
- Inhibits the mechanosensitive ion channel Piezo2.
- Inhibits [Ca2+]i elevation.
- Inhibits mTOR and PI3K-Akt signaling pathways.
- Inhibits mechanical allodynia and thermal hyperalgesia.
- Suitable for research on mechanical stress, chronic pain, and idiopathic pulmonary fibrosis.
- Decreases phosphorylation levels of proteins in the mTOR and PI3K-Akt signaling pathways in primary human lung fibroblasts.
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