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Medchemexpress LLC D-GsMTx4 | 99.44% | 4095.84 | 2 MG
SDP

Supplier:  Medchemexpress LLC HYP1410B2MG

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D-GsMTx4 is a spider peptide, serving as the D enantiomer of GsMTx4. It functions as an inhibitor of the mechanosensitive ion channel Piezo2, effectively reducing [Ca2+]i elevation and modulating the mTOR and PI3K-Akt signaling pathways. This peptide has shown to inhibit mechanical allodynia and thermal hyperalgesia, making it a valuable tool for research into conditions such as mechanical stress, chronic pain, and idiopathic pulmonary fibrosis.

  • Inhibits Piezo2-mediated mechanosensitive inward currents
  • Decreases phosphorylation levels in mTOR and PI3K-Akt pathways
  • Inhibits mechanical stimulation-evoked [Ca2+]i increases
  • Reduces mechanical allodynia and thermal hyperalgesia

Catalog No. 50-004-22961


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