D-(-)-Penicillamine, 98%

Description

CAS: 52-67-5 | C5H11NO2S | 149.208 g/mol

It is used mainly as chelating agent in heavy metal poisoning as in lead, mercury and copper poisoning. It is used in Wilson's disease. It  is used in pharmacy as chelating agent and as immunosuppressant for treating rheumatoid arthritis by reducing the number of T cells, inhibiting the macrophages, by reducing the activity of Interleukin 1 and rheumatoid factor and in preventing crosslinking of the collagen. It acts as an exogenous NOS modulator.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
It is freely soluble in water, slightly soluble in alcohol, insoluble in chloroform, ether, acetone, benzene, and in carbon tetrachloride.

Notes
Stable under normal conditions. Incompatabile to strong oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C.

Specifications

Chemical Identifiers

• CAS: 52-67-5
• Molecular Formula: C5H11NO2S
• Molecular Weight (g/mol): 149.208
• MDL Number: MFCD00064302
• InChI Key: VVNCNSJFMMFHPL-VKHMYHEASA-N
• Synonym: d-penicillamine, penicillamine, cuprimine, d---penicillamine, depen, 3-mercapto-d-valine, cuprenil, d-penamine, --penicillamine, d-mercaptovaline
• PubChem CID: 5852
• ChEBI: CHEBI:7959
• IUPAC Name: (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
• SMILES: CC(C)(C(C(=O)O)N)S

• Melting Point: 202°C to 204°C (decomposition)
• pH: 4.5 to 5.5
• Odor: Unpleasant
• Quantity: 5 g
• Beilstein: 1722375
• Merck Index: 14,7088
• Solubility Information: It is freely soluble in water,slightly soluble in alcohol,insoluble in chloroform,ether,acetone,benzene,and in carbon tetrachloride.
• Optical Rotation: −63° (c=1 in 1N NaOH)
• Formula Weight: 149.21
• Percent Purity: 99%
• Chemical Name or Material: D- (-)-Penicillamine

Safety and Handling

Hazard Category	H315-H319-H334
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P280-P285-P302+P352-P304+P341-P305+P351+P338-P332+P313-P342+P311-P362-P501c
EINECSNumber	200-148-8
RTECSNumber	YV9425000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only