Medchemexpress LLC (D)-PPA 1 TFA | 99.3% | 1669.67 | 5 MG

Supplier:  Medchemexpress LLC HYP4072A5MG

(D)-PPA 1 TFA is a hydrolysis-resistant d-peptide antagonist and a potent PD-1/PD-L1 inhibitor. It binds to PD-1 with an affinity of 0.51 μM and demonstrates both in vitro and in vivo efficacy, making it suitable for cancer immunotherapy research.

• Hydrolysis-resistant d-peptide antagonist.
• Potent PD-1/PD-L1 inhibitor.
• Binds to PD-1 with 0.51 μM affinity.
• Demonstrates in vitro and in vivo efficacy.
• Blocks the interaction between PD-1/PD-L1 at 1.0 mg/mL.
• Does not directly kill tumor cells or affect CT26 cell growth (3.125-100 μM over 24-48 hours in vitro).
• Inhibits CT26 tumor growth in mice (2 mg/kg; s.c. or i.p.; once daily for 7 d).
• Can target tumor tissue in CT26-tumor-bearing mice (40 μg/mouse in 200 μL; i.v.; single dose).
• High purity: 99.3%.
• Appearance: Solid, white to off-white.

Catalog No. 50-003-98467