Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000398467

Medchemexpress LLC (D)-PPA 1 TFA | 99.3% | 1669.67 | 5 MG
SDP

Catalog No. 5000398467
Encompass_Preferred

(D)-PPA 1 TFA is a hydrolysis-resistant d-peptide antagonist and a potent PD-1/PD-L1 inhibitor. It binds to PD-1 with an affinity of 0.51 μM and demonstrates both in vitro and in vivo efficacy, making it suitable for cancer immunotherapy research.

  • Hydrolysis-resistant d-peptide antagonist.
  • Potent PD-1/PD-L1 inhibitor.
  • Binds to PD-1 with 0.51 μM affinity.
  • Demonstrates in vitro and in vivo efficacy.
  • Blocks the interaction between PD-1/PD-L1 at 1.0 mg/mL.
  • Does not directly kill tumor cells or affect CT26 cell growth (3.125-100 μM over 24-48 hours in vitro).
  • Inhibits CT26 tumor growth in mice (2 mg/kg; s.c. or i.p.; once daily for 7 d).
  • Can target tumor tissue in CT26-tumor-bearing mice (40 μg/mouse in 200 μL; i.v.; single dose).
  • High purity: 99.3%.
  • Appearance: Solid, white to off-white.

Catalog No. 50-003-98467 Supplier Medchemexpress LLC Supplier No. HYP4072A5MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

(D)-PPA 1 TFA is a hydrolysis-resistant d-peptide antagonist and a potent PD-1/PD-L1 inhibitor. It binds to PD-1 with an affinity of 0.51 μM and demonstrates both in vitro and in vivo efficacy, making it suitable for cancer immunotherapy research.

  • Hydrolysis-resistant d-peptide antagonist.
  • Potent PD-1/PD-L1 inhibitor.
  • Binds to PD-1 with 0.51 μM affinity.
  • Demonstrates in vitro and in vivo efficacy.
  • Blocks the interaction between PD-1/PD-L1 at 1.0 mg/mL.
  • Does not directly kill tumor cells or affect CT26 cell growth (3.125-100 μM over 24-48 hours in vitro).
  • Inhibits CT26 tumor growth in mice (2 mg/kg; s.c. or i.p.; once daily for 7 d).
  • Can target tumor tissue in CT26-tumor-bearing mice (40 μg/mouse in 200 μL; i.v.; single dose).
  • High purity: 99.3%.
  • Appearance: Solid, white to off-white.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.