Cayman Chemical D-PyroaspartIc AcId 500mg

Supplier:  Cayman Chemical 31696500 MG

An orally bioavailable non-nucleoside partial adenosine receptor agonist binds selectively to human A1 and A2B (EC50s 0 66 and 1 1 nM respectively) over A2A and A3 receptors (EC50s 1413 and 240 nM respectively) expressed in CHO cells decreases electrical field-stimulated norepinephrine release from isolated perfused hearts from SHR but not from control rats at 0 6 M protects against stress-induced increases in heart rate in SHR but not control rats at 0 15 mg/kg for 5 days prior to stress induction decreases cardiac infarct size from 28 7 to 22 in a LAD-induced ischemia mouse model at 0 1 mg/kg increases LVEF in a microembolization-induced heart failure dog model at 7 5 mg twice daily

Catalog No. 50-299-0700