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Cayman Chemical D-PyroaspartIc AcId 50mg
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Supplier:  Cayman Chemical 3169650 MG

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A SIRT1 activator increases renal SIRT1 activity and protein levels and decreases acetylation of p53 in a mouse model of STZ-induced diabetes as well as in non-diabetic control animals at 100 mg/kg in the diet decreases renal levels of iNOS ROS and MDA as well as the fibrotic markers TGF-B1 and CTGF and the inflammatory markers PAI-1 and VCAM-1 in STZ-induced diabetic mice increases lifespan improves motor function in the balance beam test and reduces atrophy of the neocortex in the N171-82Q mouse model of Huntingtons disease at 0 5 in the diet

Catalog No. 50-299-2630


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