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Cayman Chemical D-Xylose 250g
SDP

Supplier:  Cayman Chemical 33236250 G

Encompass_Preferred

A GHBR antagonist (IC50s 134.1 and 201.3 nM in isolated rat striatal and hippocampal membranes respectively in radioligand binding assays) selective for GHBR over GABA binding sites in rat brain synaptic membranes at 1 and 10 UM decreases GHB-induced increases in inositol phosphate accumulation and cGMP levels in isolated rat hippocampal slices (IC50s 8.6 and 30 UM respectively) reduces GHB-induced increases in the time mice spent immobile in the forced swim test at 1.66 and 2.08 mmol/kg decreases spike and wave discharges in audiogenic seizure-susceptible Swiss Rb mice as well as a rat model of petit mal epilepsy at 2.3 mmol/kg

Catalog No. 50-294-8069


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