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Medchemexpress LLC D4-abiraterone | 154229-21-7 | 99.85% | 347.50 | 25 MG
SDP

Catalog No. 5000347356
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D4-abiraterone is a significant metabolite of abiraterone. It functions as an inhibitor of CYP17A1, 3β-hydroxysteroid dehydrogenase (3βHSD), and steroid-5a-reductase (SRD5A), and also acts as an antagonist of the androgen receptor.

  • Higher potency than abiraterone in blocking conversion of dehydroepiandrosterone (DHEA) in xenografts.
  • Demonstrates greater affinity for mutant and wild-type androgen receptor compared to abiraterone.
  • Effectively suppresses gene expression in cell lines.
  • Delays tumor progression more significantly than abiraterone acetate.
  • Purity: 99.85%.
  • Molecular Weight: 347.50.
  • Appearance: Solid, white to off-white.
  • Solubility in DMSO: 10 mg/mL (28.78 mM).

Catalog No. 50-003-47356 Supplier Medchemexpress LLC Supplier No. 25MGHY109619
May include imposed supplier surcharges.
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D4-abiraterone is a significant metabolite of abiraterone. It functions as an inhibitor of CYP17A1, 3β-hydroxysteroid dehydrogenase (3βHSD), and steroid-5a-reductase (SRD5A), and also acts as an antagonist of the androgen receptor.

  • Higher potency than abiraterone in blocking conversion of dehydroepiandrosterone (DHEA) in xenografts.
  • Demonstrates greater affinity for mutant and wild-type androgen receptor compared to abiraterone.
  • Effectively suppresses gene expression in cell lines.
  • Delays tumor progression more significantly than abiraterone acetate.
  • Purity: 99.85%.
  • Molecular Weight: 347.50.
  • Appearance: Solid, white to off-white.
  • Solubility in DMSO: 10 mg/mL (28.78 mM).

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