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Medchemexpress LLC Dabrafenib | 1195765-45-7 | MFCD17215684 | 99.94% | 519.56 | 1 ML
SDP

Catalog No. 5000363796
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Dabrafenib is an ATP-competitive inhibitor of Raf, with IC50s of 5 nM for C-Raf and 0.6 nM for B-RafV600E. This compound is intended for research purposes only and has demonstrated the ability to suppress PolyP-mediated vascular barrier permeability and inflammatory responses.

  • ATP-competitive inhibitor of Raf
  • Inhibits C-Raf with an IC50 of 5 nM
  • Inhibits B-RafV600E with an IC50 of 0.6 nM
  • Reduces S6P phosphorylation in A375 cells
  • Suppresses PolyP-mediated vascular barrier permeability
  • Downregulates HMGB1-dependent inflammatory responses

Catalog No. 50-003-63796 Supplier Medchemexpress LLC Supplier No. HY1466010MM/1ML
May include imposed supplier surcharges.
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Dabrafenib is an ATP-competitive inhibitor of Raf, with IC50s of 5 nM for C-Raf and 0.6 nM for B-RafV600E. This compound is intended for research purposes only and has demonstrated the ability to suppress PolyP-mediated vascular barrier permeability and inflammatory responses.

  • ATP-competitive inhibitor of Raf
  • Inhibits C-Raf with an IC50 of 5 nM
  • Inhibits B-RafV600E with an IC50 of 0.6 nM
  • Reduces S6P phosphorylation in A375 cells
  • Suppresses PolyP-mediated vascular barrier permeability
  • Downregulates HMGB1-dependent inflammatory responses

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