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Medchemexpress LLC Dabrafenib (mesylate) | 1195768-06-9 | 99.9% | 615.67 | 50 MG
SDP

Catalog No. 5000360913
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Dabrafenib Mesylate is a potent and selective Raf kinase inhibitor with IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively. It is intended for research use.

  • Inhibits over 90% of cell growth in NRAS mutant clones
  • Reduces S6P phosphorylation in A375 cells
  • Suppresses PolyP-mediated vascular barrier permeability
  • Downregulates HMGB1-dependent inflammatory responses
  • Enhances the expression of cell adhesion molecules (CAMs) in human endothelial cells

Catalog No. 50-003-60913 Supplier Medchemexpress LLC Supplier No. HY14660A50MG
May include imposed supplier surcharges.
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Dabrafenib Mesylate is a potent and selective Raf kinase inhibitor with IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively. It is intended for research use.

  • Inhibits over 90% of cell growth in NRAS mutant clones
  • Reduces S6P phosphorylation in A375 cells
  • Suppresses PolyP-mediated vascular barrier permeability
  • Downregulates HMGB1-dependent inflammatory responses
  • Enhances the expression of cell adhesion molecules (CAMs) in human endothelial cells

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