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Abcam Dabrafenib, mutant B-Raf V600E inhibitor, 25MG

Supplier:  Abcam AB22201925MG

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MW 519.6 Da, Purity >98%. Potent, ATP-competitive mutant B-Raf V600E inhibitor (IC50 = 0.7 nM), with selectivity versus wild-type B-Raf (IC50 = 5.2 nM) and c-RAf (IC50 = 6.3 nM) in cell-free assays. Antitumor activity *in vivo* in mouse models of B-Raf V600E melanoma.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-267-6417


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