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Cayman Chemical DAmIno ACD OxIdase InhIbIto

Supplier: Cayman Chemical 23894500 MG
An inhibitor of DAAO (IC50s = 145 and 114 nM in CHO cells expressing human and rat DAAO, respectively); selective for DAAO over a panel of 150 enzymes, receptors and ion channels (30 μM); inhibits DAAO activity in rat kidney and cerebellum in a dose- and time-dependent manner (10-200 mg/kg, i.p.); increases levels of D-serine in rat plasma and CSF; reduces formalin-induced paw flinching in rats (EC50 = 0.17 μg per animal)
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