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Enzo Life Sciences Damnacanthal (1mg). CAS: 477-84-9
Supplier: Enzo Life Sciences BMLEI2740001
Damnacanthal is a potent and selective inhibitor of p56lck tyrosine kinase. It inhibits p56lck autophosphorylation (IC50=17 nM) as well as phosphorylation of exogenous substrates (IC50=620 nM) in cell-free assays. Damnacanthal shows a 10-fold selectivity for p56lck over PKA and PKC and 40-fold selectivity over four receptor tyrosine kinases as well as 7–20-fold selectivity over the homologous enzymes p60src and p59fyn. Alternative name: 3-Hydroxy-1-methoxyanthraquinone-2-aldehyde. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
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