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Medchemexpress LLC Danegaptide Hydrochloride | 943133-81-1 | 99.5% | 327.76 | 25 MG
Supplier: Medchemexpress LLC 25MGHY10913A
Danegaptide Hydrochloride is a potent, selective, and orally active gap-junction modifier that exhibits an antiarrhythmic effect. It is intended for research use only. In vitro studies show it reduces dye uptake in cultured C6 glioma cells in a dose-dependent manner. In vivo, it prolongs the time to conduction block after CaCl2 infusion in mice and reduces atrial fibrillation in a dog model without affecting heart rate or blood pressure. This compound is an effective antiarrhythmic in ischemia/reperfusion-induced arrhythmogenesis.
- Potent, selective, and orally active gap-junction modifier
- Exhibits antiarrhythmic effect
- Reduces dye uptake in C6 glioma cells
- Prolongs time to conduction block in mice
- Reduces atrial fibrillation in dogs
- No effect on heart rate, arterial blood pressure, or ECG parameters
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