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Medchemexpress LLC Dantrolene | 7261-97-4 | MFCD00867709 | 98.4% | 314.26 g/mol | C14H10N4O5 | 10MG
Supplier: Medchemexpress LLC HY1254210MG
Dantrolene is a research-grade skeletal muscle relaxant and ryanodine receptor (RyR) inhibitor used to study calcium homeostasis, malignant hyperthermia, muscle spasm, and related neurological or ischemic conditions. It acts as a non-competitive glutathione reductase inhibitor (reported Ki 111.6 μM; IC50 52.3 μM) and inhibits Ca2+ release from RyR1 and RyR3, making it useful for biochemical and cell-based studies.
- Direct RyR1 and RyR3 calcium-release inhibitor.
- Used in research on malignant hyperthermia and muscle spasm.
- Non-competitive glutathione reductase inhibitor with reported Ki/IC50 values.
- Available in solid and solution formats suitable for assays.
- High reported purity (~98.4%).
- Molecular formula C14H10N4O5; molecular weight ~314.26 g/mol.
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