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Cayman Chemical DapIglutIdesodIum salt 10mg
Supplier: Cayman Chemical 4125910 MG
A dual GLP-1R and GLP-2R agonist; induces cAMP accumulation in HEK293 cells expressing human GLP-1R or GLP-2R (EC50s = 190 and 210 pM, respectively); reduces peak blood glucose levels in an oral glucose tolerance test and increases intestinal wet weight in mice at 6 nmol/kg; decreases gastric emptying and increases intestinal weight and length in rats (ED50s = 7.6, 20.7, and 10.7 nmol/kg, respectively); promotes body weight recovery, decreases stool water content, and increases intestinal villus height and intestinal length in a mouse model of short bowel and intestinal insufficiency induced by 40% ileocecal resection
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