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Apexbio Technology LLC Dapivirine (TMC120) 244767-67-7 10mM (in 1mL DMSO)
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Supplier:  Apexbio Technology LLC A85545.1

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Dapivirine (TMC120) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting HIV-1 viral replication By binding directly to HIV-1 reverse transcriptase dapivirine inhibits viral RNA-dependent DNA polymerase activity thus blocking viral DNA synthesis Dapivirine demonstrates activity against HIV-1 reverse transcriptase with reported IC50 values in the low nanomolar range (approximately 1-10 nM) Due to its molecular specificity and promising in vitro antiviral profile dapivirine is widely utilized in biomedical research exploring topical prevention strategies particularly in the development of vaginal microbicides aimed at reducing HIV transmission

Catalog No. 50-000-61723


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