Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000405465

Medchemexpress LLC Dapoxetine hydrochloride | 129938-20-1 | 100.0% | 1 ML
SDP

Supplier:  Medchemexpress LLC HYB0304A10MM/1ML

Encompass_Preferred

Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor (SSRI) that can be utilized for research related to premature ejaculation (PE).

  • Orally active and selective serotonin reuptake inhibitor (SSRI).
  • Applicable for research of premature ejaculation (PE).
  • Binds to 5-HT, norepinephrine, and dopamine reuptake transporters.
  • Inhibits 5-HT, norepinephrine, and dopamine uptake with an order of potency: 5-HT > norepinephrine ≈ dopamine.
  • Demonstrates an IC50 of 1.12 nM for inhibiting the uptake of [3H]5-HT by the 5-HT reuptake transporter.
  • Shows IC50 values of 202 nM and 1720 nM for inhibiting the uptake of [3H]norepinephrine and [3H]dopamine, respectively.
  • Significantly inhibits testosterone-mediated increase in prostate weight and attenuates testosterone-induced prostatic hyperplasia in rats.

Catalog No. 50-004-05465


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.