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Cayman Chemical DAPT, 208255-80-5, 5 mg

Supplier: Cayman Chemical 131975

Molecular Formula C23H26F2N2O4, Purity ≥95%, Formula Weight 432.5, Synonyms: N-[2S-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-1,1-dimethylethyl ester-glycine, GSI-IX; An inhibitor of -secretase, blocking the production of total A in human primary neuronal cultures with an IC50 value of 115 nM and A42 with an IC50 value of 200 nM; reduces brain levels of A in vivo when given orally; indirectly inhibits Notch, affecting cell signaling and cell differentiation.
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