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Medchemexpress LLC Dasotraline (hydrochloride) | 675126-08-6 | 99.04% | 1 ML
SDP

Catalog No. 5000338268
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Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.

  • Blocks dopamine, norepinephrine, and serotonin transporters.
  • Exhibits high potency with IC50 values of 4 nM for dopamine, 6 nM for norepinephrine, and 11 nM for serotonin.
  • Inhibits spontaneous firing rates of LC NE, VTA DA, and DR 5-HT neurons.
  • Equipotently inhibits 5-HT and NE transporters.
  • Used in research for neuronal signaling pathways.
  • Applicable in studies on monoaminergic neurons.
  • Utilized for investigations into dopamine and serotonin transporter occupancy.

Catalog No. 50-003-38268 Supplier Medchemexpress LLC Supplier No. HY12850A10MM/1ML
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Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.

  • Blocks dopamine, norepinephrine, and serotonin transporters.
  • Exhibits high potency with IC50 values of 4 nM for dopamine, 6 nM for norepinephrine, and 11 nM for serotonin.
  • Inhibits spontaneous firing rates of LC NE, VTA DA, and DR 5-HT neurons.
  • Equipotently inhibits 5-HT and NE transporters.
  • Used in research for neuronal signaling pathways.
  • Applicable in studies on monoaminergic neurons.
  • Utilized for investigations into dopamine and serotonin transporter occupancy.

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