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Medchemexpress LLC Datelliptium (chloride) | 105118-14-7 | 397.94 | 100 MG
Supplier: Medchemexpress LLC HYU00337100MG
Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, exhibiting anti-tumor activities. It is intended for research use only and not for patient use. In vitro, it shows cytotoxic effects in rat hepatocytes, mobilizing glycogen and decreasing gluconeogenesis. In vivo, it demonstrates potent inhibitory activities against various murine solid tumors.
- Exhibits cytotoxic effects on suspension and primary cultures of rat hepatocytes.
- Mobilizes glycogen in rat systems in vitro concentration-dependently.
- Causes a concentration-dependent decrease in gluconeogenesis from lactate in cells.
- Selectively cytotoxic for solid tumors over leukemia L1210.
- Demonstrates potent inhibitory activities against various murine solid tumors.
- Highly active against early-stage colon #38.
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