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Apexbio Technology LLC Daunorubicin 20830-81-3 10mg
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Supplier:  Apexbio Technology LLC B109910

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Daunorubicin (20830-81-3) is a small-molecule inhibitor targeting DNA topoisomerase II It is designed to inhibit this target thereby disrupting nucleic acid synthesis within tumor cells Daunorubicin exerts its biological activity primarily through stabilizing the topoisomerase II-DNA cleavage complex interfering with DNA replication and transcription In in vitro studies daunorubicin demonstrates inhibition of metabolic incorporation of nucleoside precursors into DNA and RNA with reported IC50 values for inhibition of leukemia cell growth ranging from 0 02 1 M depending on cellular context and assay conditions Based on these pharmacological properties daunorubicin holds research potential in oncology studies related to chemotherapy-induced genotoxicity and nucleic acid metabolism

Catalog No. 50-000-89116


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