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Medchemexpress LLC Daunorubicin hydrochloride | 23541-50-6 | 99.7% | 200 MG
Supplier: Medchemexpress LLC HY13062200MG
Daunorubicin hydrochloride is a potent topoisomerase II inhibitor and anthracycline antibiotic with significant anti-tumor activity. It inhibits DNA and RNA synthesis, acting as a cytotoxin that reduces cancer cell viability and induces apoptosis and necrosis. It is used in research for various cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, and Wilms' tumor, as well as infection studies.
- Inhibits DNA and RNA synthesis in sensitive and resistant Ehrlich ascites tumor cells.
- Exhibits chemosensitivity in Molt-4 and L3.6 cells.
- Induces apoptosis and necrosis in L3.6 cells.
- Triggers ROS generation in L3.6 cells.
- Induces autophagy in K562 cells.
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