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Medchemexpress LLC Dazostinag disodium (TAK-676) | 2553413-93-5 | 98.65% | 754.48 | 100 UG
SDP

Supplier:  Medchemexpress LLC HY148029100UG

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Dazostinag disodium (TAK-676) is a STING agonist that activates the STING signaling pathway and type I interferons. It also modulates the immune system, leading to complete regressions and durable memory T-cell immunity, promoting durable IFN-dependent antitumor immunity.

  • Activates the STING-TBK1-IRF3 pathway.
  • Modulates immune cells, including dendritic, natural killer, and T cells (CD8+, CD4+).
  • Well tolerated with dose-proportional pharmacokinetics.
  • Demonstrates anti-tumor function in syngeneic tumor models.
  • Induces cytokine responses and increases activation and proliferation of immune cells.

Catalog No. 50-003-61336


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