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Medchemexpress LLC Dbco-conh-s-s-nhs ester | 1435934-53-4 | MFCD22380758 | 99.2% | 565.66 g/mol | C28H27N3O6S2 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1334135MG

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DBCO-CONH-S-S-NHS ester is a cleavable disulfide-containing ADC linker that combines a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC) with an N-hydroxysuccinimide (NHS) activated ester for conjugation to amines.

  • Provides a cleavable disulfide spacer for controlled payload release.
  • Enables copper-free click chemistry via DBCO for bioorthogonal conjugation.
  • Contains an NHS-activated ester for efficient amine coupling.
  • High reported purity supports sensitive bioconjugation workflows.
  • Soluble in DMSO at high concentrations for easy handling and stock preparation.
  • Stable when stored protected from light and under inert atmosphere at low temperatures.

Catalog No. 50-002-02574


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