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Medchemexpress LLC DBCO-mPEG (MW 5kDa) | 99.1% | 25 MG
Supplier: Medchemexpress LLC 25MGHY140319
DBCO-mPEG (MW 5kDa) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring a DBCO group capable of strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs utilize the intracellular ubiquitin-proteasome system for the selective degradation of target proteins by connecting an E3 ubiquitin ligase ligand and a specific protein target ligand with a linker.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains a DBCO group for SPAAC with azide groups
- Used in the synthesis of PROTACs
- Leverages the ubiquitin-proteasome system for selective protein degradation
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