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Medchemexpress LLC DBCO-NH-Boc | 1539290-74-8 | C23H24N2O3 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14029350MG

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DBCO-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

  • Alkyl/ether-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Click chemistry reagent
  • Contains a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups
  • Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins

Catalog No. 50-003-57334


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