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Medchemexpress LLC DBCO-PEG12-NHS ester | 2093934-94-0 | 96.12% | C50H71N3O18 | 100 MG
Supplier: Medchemexpress LLC HY140274100MG
DBCO-PEG12-NHS ester is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, utilizing a DBCO group to facilitate strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. PROTACs leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Enables synthesis of PROTACs
- Functions as a click chemistry reagent
- Utilizes DBCO group for SPAAC with azide-containing molecules
- Supports selective degradation of target proteins
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