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Medchemexpress LLC DBCO-PEG2-acid | 2304558-25-4 | ≥95.0% | C26H28N2O6 | 250 MG
Supplier: Medchemexpress LLC 250MGHY140266
DBCO-PEG2-acid is a PEG-based PROTAC linker designed for synthesizing PROTACs. It acts as a click chemistry reagent, featuring a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. PROTACs typically comprise two distinct ligands connected by a linker, where one targets an E3 ubiquitin ligase and the other targets the protein of interest, enabling selective degradation through the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Click chemistry reagent
- Incorporates a DBCO group
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Used in the synthesis of PROTACs
- Leverages the intracellular ubiquitin-proteasome system
- Suitable for laboratory chemical applications
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