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Medchemexpress LLC Dbco-(PEG2-VC-PAB-MMAE)2 | 2259318-55-1 | 99.2% | 2,835.50 g/mol | C149H224N22O32 | 50 MG
Supplier: Medchemexpress LLC HY12669050MG
DBCO-(PEG2-VC-PAB-MMAE)2 is a drug-linker conjugate for antibody-drug conjugate (ADC) research that combines a DBCO reactive group with a cleavable valine-citrulline linker, a p-aminobenzyl self-immolative spacer, and dual MMAE payloads. It is supplied as a purified powder for use in bio-conjugation via strain-promoted alkyne-azide cycloaddition (SPAAC).
- Provides a DBCO reactive group for copper-free click chemistry (SPAAC).
- Includes a PEG2 spacer for improved solubility and flexibility.
- Features a valine-citrulline cleavable linker with a p-aminobenzyl self-immolative spacer.
- Contains two MMAE payloads for potent cytotoxic delivery.
- High purity, typically 99.2%.
- Supplied as a powder suitable for ADC construction and conjugation.
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