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Medchemexpress LLC Dbco-PEG3-Glu-VC-PABC-MMAF | 2253947-24-7 | 1743.05 g/mol | C90H127N13O22 | 5 MG
SDP

Catalog No. 5000263037
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DBCO-PEG3-Glu-VC-PABC-MMAF is a synthetic drug-linker conjugate intended for antibody-drug conjugate research and bioconjugation. It integrates a DBCO click handle, a three-unit PEG spacer, and a Glu-Val-Cit-PABC cathepsin-cleavable linker to deliver the cytotoxic MMAF payload upon intracellular cleavage. Supplied as a solid for use in ADC synthesis workflows.

  • Click-chemistry compatible DBCO group enables strain-promoted alkyne-azide cycloaddition (SPAAC).
  • Three-unit PEG spacer improves solubility and reduces steric hindrance.
  • Glu-Val-Cit-PABC linker is cleavable by cathepsins for intracellular payload release.
  • Includes MMAF payload for potent tubulin inhibition after release.
  • Provided as a solid suitable for storage and handling in ADC synthesis workflows.

Catalog No. 50-002-63037 Supplier Medchemexpress LLC Supplier No. HY1311585MG
May include imposed supplier surcharges.
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DBCO-PEG3-Glu-VC-PABC-MMAF is a synthetic drug-linker conjugate intended for antibody-drug conjugate research and bioconjugation. It integrates a DBCO click handle, a three-unit PEG spacer, and a Glu-Val-Cit-PABC cathepsin-cleavable linker to deliver the cytotoxic MMAF payload upon intracellular cleavage. Supplied as a solid for use in ADC synthesis workflows.

  • Click-chemistry compatible DBCO group enables strain-promoted alkyne-azide cycloaddition (SPAAC).
  • Three-unit PEG spacer improves solubility and reduces steric hindrance.
  • Glu-Val-Cit-PABC linker is cleavable by cathepsins for intracellular payload release.
  • Includes MMAF payload for potent tubulin inhibition after release.
  • Provided as a solid suitable for storage and handling in ADC synthesis workflows.

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