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Medchemexpress LLC DBCO-PEG3-NHS ester | 2163772-16-3 | 98.5% | 605.64 g/mol | C32H35N3O9 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY15650710MG

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DBCO-PEG3-NHS ester is a PEG-spaced dibenzocyclooctyne (DBCO) reagent bearing an N-hydroxysuccinimide (NHS) ester. It is designed for copper-free click conjugation of azide-functionalized payloads to primary amines and is commonly used as a linker in bioconjugation workflows such as antibody-drug conjugate synthesis.

  • Enables copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing partners.
  • Contains an NHS ester reactive toward primary amines for facile conjugation.
  • Peg3 spacer improves solubility and reduces steric hindrance at the conjugation site.
  • Suitable for bioconjugation workflows, including linker installation for antibody-drug conjugates.
  • Provided at high reported purity for reproducible conjugation performance.

Catalog No. 50-002-88046


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