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Medchemexpress LLC DBCO-PEG4-C2-acid | 1537170-85-6 | 99.2% | 250 MG
SDP

Supplier:  Medchemexpress LLC 250MGHY130396

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DBCO-PEG4-C2-acid is a PEG-based PROTAC linker used in PROTAC synthesis. It is a click chemistry reagent with a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. PROTACs, which contain two different ligands connected by a linker (one for an E3 ubiquitin ligase and one for the target protein), utilize the intracellular ubiquitin-proteasome system for selective target protein degradation.

  • Utilized in the synthesis of PROTACs
  • Functions as a click chemistry reagent
  • Contains a DBCO group
  • Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
  • Reacts with azide groups in molecules

Catalog No. 50-003-41557


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