Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC DBCO-PEG4-PFP ester | 95.0% | C36H35F5N2O8 | 25 MG
Supplier: Medchemexpress LLC 25MGHY140278
DBCO-PEG4-PFP ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, incorporating a DBCO group capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. PROTACs are composed of two ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other the protein of interest. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based protac linker
- Used in protac synthesis
- Functions as a click chemistry reagent
- Incorporates a dbco group
- Undergoes strain-promoted alkyne-azide cycloaddition (spaac) with azide groups
- Leverages the ubiquitin-proteasome system
- Selectively degrades target proteins
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?