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Medchemexpress LLC Dbco-PEG4-Val-Cit-PAB-MMAF | 2244602-23-9 | 98.7% | 1672.01 | C88H126N12O20 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY13099010MG

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DBCO-PEG4-Val-Cit-PAB-MMAF is a cleavable ADC linker-payload conjugate that pairs a DBCO-functionalized PEG4 Val-Cit-PAB linker with the tubulin inhibitor MMAF. It is provided as a solid for use in antibody-drug conjugate synthesis and copper-free click chemistry (SPAAC) with azide-containing biomolecules. The Val-Cit-PAB spacer is designed for cathepsin-mediated cleavage to release the payload under lysosomal conditions.

  • Cleavable Val-Cit-PAB spacer for enzymatic release.
  • DBCO handle for copper-free click (SPAAC) conjugation.
  • Hydrophilic PEG4 spacer improves solubility and flexibility.
  • High reported purity suitable for research conjugation workflows.
  • Available in small milligram pack sizes for lab-scale synthesis.

Catalog No. 50-002-03343


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