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Medchemexpress LLC DBCO-PEG4-Val-Cit-PAB-PNP | 2226472-28-0 | 97.3% | 1079.16 | C55H66N8O15 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYW1909135MG

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DBCO-PEG4-Val-Cit-PAB-PNP is a cleavable antibody-drug conjugate (ADC) linker for research-scale conjugation. It features a DBCO click handle, a four-unit PEG spacer, a valine-citrulline protease-cleavable dipeptide, and a PAB/PNP leaving group to enable intracellular payload release after protease cleavage. Supplied as a solid for conjugation to azide-functionalized payloads and carriers.

  • Contains DBCO click handle for strain-promoted azide-alkyne cycloaddition.
  • Includes PEG4 spacer to increase hydrophilicity and reduce aggregation.
  • Val-Cit dipeptide is cleavable by cathepsin B for intracellular payload release.
  • PAB/PNP leaving group enables efficient payload release after cleavage.
  • High purity suitable for research applications.
  • Solid, off-white to light yellow appearance; store at -20°C and protect from light.

Catalog No. 50-002-81803


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