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Medchemexpress LLC Dbco-PEG4-VC-PAB-DMEA-PNU-159682 | 2259318-56-2 | 1695.81 g/mol | C86H106N10O26 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY1266911MG

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DBCO-PEG4-VC-PAB-DMEA-PNU-159682 is an ADC linker-drug conjugate designed for antibody-drug conjugate synthesis and click-chemistry conjugation. It contains a DBCO group for strain-promoted alkyne-azide cycloaddition, a four-unit PEG spacer for solubility, a valine-citrulline cleavable dipeptide with a para-aminobenzyl self-immolative spacer, and a DMEA-modified PNU-159682 payload.

  • Facilitates SPAAC (strain-promoted alkyne-azide cycloaddition) for bioorthogonal conjugation.
  • PEG4 spacer improves solubility and reduces steric hindrance.
  • Val-Cit-PAB linker enables protease-cleavable payload release.
  • Includes a potent PNU-159682-based payload for ADC research applications.
  • Supplied in small research quantities suitable for conjugation studies.

Catalog No. 50-002-03215


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