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Medchemexpress LLC Dbco-PEG4-VC-PAB-MMAE | 2129164-91-4 | 99.2% | 1658.03 | C88H128N12O19 | 25 MG
SDP

Supplier:  Medchemexpress LLC HY13631425MG

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DBCO-PEG4-VC-PAB-MMAE is a drug-linker conjugate designed for antibody-drug conjugate (ADC) synthesis and click-chemistry bioconjugation. It combines a DBCO click handle, a PEG4 spacer, a Val-Cit-PAB cleavable linker, and an MMAE cytotoxic payload, and is supplied as a solid powder for laboratory use.

  • Contains a DBCO handle for strain-promoted alkyne-azide cycloaddition (SPAAC).
  • Includes a hydrophilic PEG4 spacer to improve solubility and reduce aggregation.
  • Features a valine-citrulline (Val-Cit) peptide and para-aminobenzyl (PAB) self-immolative linker for enzymatic cleavage.
  • Delivers an MMAE warhead suitable for construction of cleavable ADCs.
  • Supplied as a white to off-white solid with recommended storage at -20°C and limited stability in solution.

Catalog No. 50-002-02595


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