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Medchemexpress LLC Dbco-PEG5-NHS ester | 2144395-59-3 | 693.74 g/mol | C36H43N3O11 | 50 MG

Supplier: Medchemexpress LLC HY12688550MG
Dbco-PEG5-NHS ester is a heterobifunctional, PEG-based bioorthogonal linker that combines a dibenzocyclooctyne (DBCO) moiety for strain-promoted alkyne-azide cycloaddition with an N-hydroxysuccinimide (NHS) ester for selective coupling to primary amines. It is intended for use in bioconjugation workflows such as antibody-drug conjugate and PROTAC synthesis, and for copper-free click chemistry and surface labeling.
- Enables copper-free click conjugation to azide-containing molecules via the DBCO group.
- Allows rapid amine coupling through the NHS ester at pH 7-9.
- PEG5 spacer improves solubility and reduces steric hindrance.
- Supplied as a small-scale reagent suitable for research and development work.
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