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Medchemexpress LLC DBCO-PEG5-NHS ester | 2144395-59-3 | 95.0% | 693.74 | C36H43N3O11 | 25 MG
Supplier: Medchemexpress LLC HY12688525MG
DBCO-PEG5-NHS ester is a DBCO-functionalized PEG linker with an N-hydroxysuccinimide (NHS) ester reactive group. It acts as a click chemistry reagent enabling strain-promoted alkyne-azide cycloaddition (SPAAC) and serves as a PEG-based linker for the synthesis of PROTACs and antibody-drug conjugates (ADCs).
- Enables copper-free click chemistry (SPAAC) with azide-containing molecules.
- Reactive NHS ester couples efficiently to primary amines, such as lysine residues or aminosilane-coated surfaces.
- PEG5 spacer provides flexibility and reduces steric hindrance at conjugation sites.
- Suitable for linker design in PROTAC and ADC synthesis.
- Available in small milligram pack sizes for research-scale applications.
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