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Medchemexpress LLC Dbco-s-s-peg3-biotin | 1430408-09-5 | MFCD28334542 | 96.9% | 869.12 g/mol | C42H56N6O8S3 | 5 MG
Supplier: Medchemexpress LLC HY1401285MG
DBCO-S-S-PEG3-biotin is a PEG-based cleavable biotinylation reagent for copper-free click chemistry and PROTAC linker synthesis. It combines a DBCO reactive moiety with a disulfide-containing PEG3 spacer to enable strain-promoted alkyne-azide cycloaddition and reductive release of the biotin tag.
- Contains a DBCO group enabling copper-free strain-promoted alkyne-azide cycloaddition (SPAAC).
- Includes a disulfide cleavable linker for release under reducing conditions.
- Features a PEG3 spacer to improve solubility and reduce steric hindrance.
- Provides a biotin tag for affinity capture and purification workflows.
- Soluble in DMSO at high concentration and compatible with common formulation protocols.
- Supplied as a colorless to off-white solid with high purity.
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