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DBeQ, Tocris Bioscience™

Catalog No. 441750
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50 mg
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Catalog No. Quantity
44-175-0 50 mg
44-171-0 10 mg
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Catalog No. 44-175-0 Supplier R&D Systems Supplier No. 4417/50
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Description

Selective and reversible p97 ATPase inhibitor

Selective and reversible inhibitor of p97 ATPase (VCP, IC50 = 1.5 μM). Induces executioner caspases (caspase-3 and caspase-7) rapidly. Blocks the degradation of endoplasmic reticulum-associated degradation (ERAD) reporters; also blocks autophagosome maturation and promotes accumulation of LC3-II.

Chemical Identifiers

CAS 177355-84-9
Molecular Formula C22H20N4
Molecular Weight (g/mol) 340.43
MDL Number MFCD03691820
InChI Key QAIMUUJJAJBPCL-UHFFFAOYSA-N
Synonym dbeq, n2,n4-dibenzylquinazoline-2,4-diamine, n,n'-dibenzylquinazoline-2,4-diamine, 2,4-dibencilaminoquinazoline, 2,4-quinazolinediamine, n,n'-bis phenylmethyl, n*2*,n*4*-dibenzyl-quinazoline-2,4-diamine, n2,n4-bis phenylmethyl-2,4-quinazolinediamine, jrf12, jrf 12, jrf-12
PubChem CID 676352
IUPAC Name N2,N4-dibenzylquinazoline-2,4-diamine
SMILES C(NC1=NC(NCC2=CC=CC=C2)=C2C=CC=CC2=N1)C1=CC=CC=C1

Specifications

Quantity 50 mg
Formula Weight 340.42
Percent Purity >99%
Chemical Name or Material DBeQ

Safety and Handling

Recommended Storage Store at +4°C
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