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ABclonal Technology DC-SIGNR/CD299 Rabbit mAb
Supplier: ABclonal Technology A2312120UL
This gene encodes a C-type lectin involved in cell adhesion and pathogen recognition It recognizes a variety of pathogens including tuberculosis mycobacteria and viruses like Ebola HIV-1 influenza A West Nile virus and SARS-CoV The protein has four domains a C-terminal carbohydrate recognition domain a flexible neck domain a transmembrane region and an N-terminal cytoplasmic domain for internalization It is closely related to CD209 (DC-SIGN) with differences in viral recognition and expression This gene is highly expressed in liver endothelial cells lymph nodes and placenta Polymorphisms in the neck domain are linked to resistance to SARS infection
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