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Selleck Chemical LLC DCA
Supplier: Selleck Chemical LLC S86151G
DCA (Sodium dichloroacetate) a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 M for PDK2 and PDK4 respectively has been shown to derepress Na -K -2Cl- cotransporter and a mitochondrial potassium-ion channel axis Sodium dichloroacetate increases reactive oxygen species (ROS) generation triggers apoptosis in cancer cells and inhibits tumor growth
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