Invitrogen™ Human DCAMKL2 (DCK2), GST Tag Recombinant Protein

Catalog No.	Quantity
PV4297	10 μg

Catalog No. PV4297 Supplier Invitrogen™ Supplier No. PV4297

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

DCAMKL2 is a serine/threonine kinase involved in signal transduction and cellular communication, and is the human homolog of a rat protein kinase expressed in cerebrocortical lamination that binds microtubules. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

Specifications

• Accession Number: Q8N568
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris HCl with 0.02% Triton X-100, 50% glycerol, 0.5mM EDTA, 2mM DTT, 150mM NaCl and no preservative; pH 7.5
• Gene ID (Entrez): 166614
• Molecular Weight (g/mol): 103.6 kDa
• Name: Human DCAMKL2 (DCK2), GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 6330415M09Rik; AU044875; CaMK-like CREB regulatory kinase 2; CL2; CLICK2; Click-II; CLIK2; DCAMKL2; DCDC3; DCDC3B; DCK2; DCLK2; doublecortin and CaM kinase-like 2; doublecortin domain-containing protein 3B; doublecortin kinase 2; doublecortin like kinase 2; doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2; RGD1308384; Serine/threonine-protein kinase DCLK2
• Common Name: DCAMKL2
• Gene Symbol: DCLK2
• Kinase Family: DCAMKL Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: Full length
• Content And Storage: Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol
  Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
• Assay Entry: Biochemical phospho-specific activity (no antibody)
• Kinase Group: Ser⁄Thr Kinases: CAMK Group
• Shipping Condition: Dry Ice
• System Compatibility: Zin-LYTE™
• Target Entry: DCAMKL2
• Target Gene: doublecortin-like kinase 2
• Expression System: Baculovirus
• Protein Family: Kinases & Inhibitors
• Protein Form: Full Length, Recombinant
• Form: Liquid
• Protein Subtype: Serine⁄Threonine Kinases
• Research Category: Signal Transduction
• Purity or Quality Grade: 85% by SDS-PAGE