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Medchemexpress LLC DCP-LA (FR236924) | 28399-31-7 | 98.0% | 308.50 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY10859910MM/1ML

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DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε. It activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. Additionally, DCP-LA inhibits activation of caspase-3/-9 and offers protection to neurons from oxidative stress-induced apoptosis.

  • Selectively and directly activates PKCε.
  • Activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII).
  • Inhibits protein phosphatase-1 (PP-1).
  • Stimulates AMPA receptor exocytosis.
  • Inhibits activation of caspase-3/-9.
  • Protects neurons from oxidative stress-induced apoptosis.
  • Facilitates hippocampal synaptic transmission.
  • Prevents SNP-induced neuronal cell death.
  • Abolishes caspase-3/9 activation.
  • Exhibits protective effect against ischemic brain damage.

Catalog No. 50-003-44312


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