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Medchemexpress LLC Dde Biotin-PEG4-DBCO | 1807512-43-1 | 96.17% | C47H61N5O9S | 100 MG
SDP

Supplier:  Medchemexpress LLC HY140931100MG

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Dde Biotin-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs consist of two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Click chemistry reagent
  • Contains a DBCO group
  • Enables strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that have azide groups
  • Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins

Catalog No. 50-003-54589


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