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Medchemexpress LLC DDO-2213 | 2378768-36-4 | C24H27ClFN7O | 5 MG
Supplier: Medchemexpress LLC HY1533315MG
DDO-2213 is an orally active and potent WDR5-MLL1 inhibitor, with an IC50 of 29 nM and a Kd value of 72.9 nM for the WDR5 protein. It selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity and the proliferation of MLL translocation-harboring cells. DDO-2213 can be used for MLL fusion leukemia research.
- Orally active
- Potent WDR5-MLL1 inhibitor
- Selectively inhibits MLL histone methyltransferase activity
- Inhibits proliferation of MLL translocation-harboring cells
- Useful for MLL fusion leukemia research
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